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, Kario, K

This makes people feel full and eat less, which helps with weight loss

Some users describe modestly higher work capacity extra reps at the same load, faster between-set recovery

Katsel, E

In these two highly excitable tissues that can undergo rapid changes in their membrane potentials for the transport of electrical signals, creatine decreases intracellular calcium concentrations (e.g., by stimulating sarcoplasmic reticulum Ca 2+ -ATPase in skeletal muscle) and extracellular glutamate concentrations (e.g., through uptake by synaptic vesicles in the brain), and prevents the opening of the mitochondrial permeability transition pore (Bender et al