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Even in long-term studies where subjects used PT-141 multiple times weekly for months, no pigmentation changes were documented

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High-risk patients may benefit from a 24-hour liquid diet before procedures, and coordination with anesthesia providers is essential

70 These changes reduce short-chain fatty acid (SCFA) production and increase secondary bile acid formation, both of which compromise gut barrier integrity

Use of Chelation Agents: If a subject is undergoing chelation therapy to remove heavy metals from the body, using GHK-Cu is counterproductive and potentially confusing for the system