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Many patients describe tingling in the toes, a buzzing sensation in the feet, or intermittent numbness that comes and goes

Researchers examining potential neurological or cognitive effects often prefer the nasal route because it provides more direct access to the central nervous system

doi: 10.1007/s11011-019-00504-2 94

Initially approved for glycemic control in type 2 diabetes mellitus, their clinical application has expanded into obesity management, cardiovascular risk reduction, and metabolic syndrome modulation