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These medications undergo rigorous clinical trials demonstrating efficacy and safety before receiving MHRA approval

The consultation included an honest discussion of where the evidence was strong (topical applications, tissue repair contexts) and where it was thinner (systemic injectable use for aesthetic outcomes)

Lage SL, Amaral EP, Hilligan KL, Laidlaw E, Rupert A, Namasivayan S, et al

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A warning can found in the label as well (GLP-1 agonists may not be used in people with history or family history of medullary thyroid cancer or certain endocrine conditions, like Multiple Endocrine Neoplasias)