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MECHANISM CATEGORIES SAFETY Side effects Generally well-tolerated in trials at the doses tested Injection-site reactions Known interactions Not characterized in Phase 3 Contraindications Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Not FDA-approved as a drug

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Ingredients that are on the FDA negative list also cannot be used as active ingredients for human compounding unless a specific route or dose is allowed on the list, as is the case with oral doses of diethylstilbestrol under 25 mg

People with more mechanical or non-inflammatory pain from osteoarthritis or an injury will have a few minutes of morning stiffness and pain that is worsened by activity