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The right dose is the one that produces meaningful results with manageable side effects

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In the present investigation, MTX challenge induced ER stress and UPR mainly through the PERK/CHOP pathway, consistent with previous studies on MTX-induced hepatic injury (Schmidt et al., 2022), nephrotoxicity (Song et al., 2021), and cognitive impairment (Lv et al., 2020)

Known for naturally existing in the body, Glutathione is a powerful substance that plays a vital role in multiple biological processes, such as detoxification and the neutralisation of free radicals

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