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(3) increased likelihood of DNA damage caused by mitochondrial dysfunction-induced oxidative stress

The higher proton leak may give a hint at mitochondrial adaptation to protect the cells from the formation of reactive oxygen species (ROS), potentially induced by a higher electron flux (49)

Chemicals and reagents El-Nasr Pharmaceutical Chemicals (Cairo, Egypt), provided a selection of analytical-grade chemicals, including ethyl acetate, acetic acid, and formic acid