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In experimental systems, the complex provides a controlled way to study copper-linked changes in collagen-associated pathways, inflammatory mediators, and oxidative stress markers
Hum Pathol 2008
As the food intake decreases, the weight reduces
65 Exendin-4, a GLP-1 analog, showed cardioprotective properties in a diabetic animal model by preventing heart remodeling and diastolic dysfunction
Protein oxidation causes odd protein structure and function, involving enzyme inactivation and distublance of cell signal transduction, straightly influencing the activity of fibroblasts and osteoblasts (Sharifi-Rad et al., 2020), ( Moreover, DNA damage activates stress response mechanisms within cells, possibly causing apoptosis or mutation, further compromising the health of gingival tissues ( 2.3.3 Depletion of antioxidant systems During the prolonged progression of chronic periodontitis, oxidative stress persists, causing depletion and imbalance of antioxidant systems (Shang et al., 2023)
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