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In terms of side effects and tolerability, the advantage goes to CagriSema
From a dietary perspective, the following principles are recommended, consistent with the NHS Eatwell Guide: Eat regular, balanced meals do not skip meals, as this can worsen nausea and lead to overeating later Reduce portion sizes gradually the medication will help with satiety, but mindful eating remains important Limit ultra-processed foods, sugary drinks, and high-fat snacks these can exacerbate gastrointestinal side effects and undermine calorie reduction Prioritise protein and fibre these nutrients support satiety and help preserve lean muscle mass during weight loss Stay well hydrated aim for pale-yellow urine as a guide