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Malignant melanotic nerve sheath tumors account for less than 1% of all primary peripheral nerve sheath tumors and most often arise from the spinal nerves or visceral autonomic nerves ( MMNST has historically been regarded as an atypical variant of schwannoma and, due to its pigmentation, has been referred to as melanotic schwannoma ( In some series, over 50% of patients with MMNSTs have evidence of Carney complex, an autosomal dominant, occasionally familial multiple neoplasia syndrome (31)

Will other medications follow suit

Philp and colleagues (FASEB J, 2003) showed the LKKTETQ site alone is sufficient to promote endothelial cell migration and angiogenesis in aortic ring and chick chorioallantoic assays, and Sosne and colleagues (FASEB J, 2010) mapped further activities onto short internal sequences of the parent protein

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