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People with certain health issues like thyroid cancer, gastroparesis, or a history of pancreatitis, and some other specific conditions

This may then promote growth of a second primary breast cancer by entering the blood stream and acting in an endocrine fashion 94, 97

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GHK-Cu is a copper-chelated tripeptide with distinct mechanisms Advantages Broader preclinical evidence base across multiple organ systems Disadvantages No topical cosmetic applications, not naturally occurring in plasma Matrixyl (Palmitoyl Pentapeptide-4)Moderate - Both used in anti-aging skincare Differences Matrixyl is a synthetic pentapeptide signaling fragment