Calocurb, a New Zealand-based dietary supplement brand that recently launched in the U.S., features the active ingredient Amarasate, a bitter extract from a specific New Zealand-grown hops flower
Once or twice daily
In an in vitro model system, a cumulative 26% of the supplemented apigenin was absorbed by intestinal epithelium over 240 min and extensive phase I and II metabolism occurred yielding apigenin metabolites, mainly apigenin-7-sulfate, attributing to apigenins low overall bioavailability [152]
*Correspondence: Liyong Zhu, [email protected] These authors have contributed equally to this work This article was submitted to Molecular Medicine, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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