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However, the unique characteristics of diseases and individual patients result in heterogeneous treatment options 2

12 CLINICAL PHARMACOLOGY CLINICAL PHARMACOLOGY SECTION 13 NONCLINICAL TOXICOLOGY NONCLINICAL TOXICOLOGY SECTION 14 CLINICAL STUDIES CLINICAL STUDIES SECTION 16 HOW SUPPLIED/STORAGE AND HANDLING HOW SUPPLIED SECTION WEGOVY Injection How Supplied WEGOVY injection is a clear, colorless solution available in cartons containing 4 single-dose pens, 4 single-dose syringes with integrated needles, or 1 single-patient-use pen (WEGOVY FlexTouch) as follows: Device Type Name Total Strength per Total Volume NDC Single-dose Pen WEGOVY 0.25 mg/0.5 mL 0169-4525-14 Single-dose Pen 0.5 mg/0.5 mL 0169-4505-14 Single-dose Pen 1 mg/0.5 mL 0169-4501-14 Single-dose Pen 1.7 mg/0.75 mL 0169-4517-14 Single-dose Pen 2.4 mg/0.75 mL 0169-4524-14 Single-dose Pen WEGOVY HD 7.2 mg/0.75 mL 0169-4572-14 Single-patient-use Pen (with 4 weekly doses of 2.4 mg) WEGOVY FlexTouch 9.6 mg/3 mL (3.2 mg/mL) 0169-4915-32 Single-dose Syringe WEGOVY 0.25 mg/0.5 mL 0169-1602-14 Single-dose Syringe 0.5 mg/0.5 mL 0169-1605-14 Single-dose Syringe 1 mg/0.5 mL 0169-1610-14 Single-dose Syringe 1.7 mg/0.75 mL 0169-1617-14 Single-dose Syringe 2.4 mg/0.75 mL 0169-1624-14 Recommended Storage Do not store WEGOVY in the freezer or directly adjacent to the refrigerator cooling element

Results build progressively over time

GLP-1 agonists mediate the stimulation of insulin secretion, delay gastric emptying, and enhance satiety

In addition, PsN Version 4.60 (University of Uppsala, was used as the interface for bootstrapping, search for global minima and creation of visual predictive checks