Age-related changes in the global DNA methylation profile of leukocytes are linked to nutrition but are not associated with the MTHFR C677T genotype or to functional capacities
Recently, California implemented stricter rules limiting coverage for GLP-1 medications such as Zepbound, Wegovy, and Saxenda when they are prescribed primarily for weight management
Both perspectives have merit depending on your goals, your response to the medication, and your ability to sustain behavioral changes
Quick notelean mass, muscle, function, etc are a concern with all routes to weight loss not just GLP-1 Lean mass is not the same as skeletal muscle When a DXA scan, bioelectrical impedance scale, or clinical trial reports lean mass, it is not measuring skeletal muscle alone
Therefore, understanding and assessing individual knee morphology is vital in predicting OA risk and optimizing preventive or surgical strategies