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Your body needs to adapt to the rhythm of frequent small meals before appetite suppression intensifies

And they may want to follow you more closely or consider adjusting the dose of your medication

People may microdose GLP-1 medications for many reasons, including: They have hit their target weight goal They have concerns about the cost of the medications They are sensitive to the side effects of the medications They want to just suppress their appetite They are worried about the supply of the medications Microdosing GLP-1 medications can come with real risks, including: Inaccurate doses Reduced effectiveness Unpredictable outcomes Possibility of regaining weight No data on the long-term effects of microdosing Minimal oversight Large clinical trials have confirmed that the standard GLP-1 doses work well when helping people lose weight and manage Type 2 diabetes

"Mitochondrial control of fuel switching via carnitine biosynthesis," Science, Vol 391, Issue 6786, (10.1126/science.ady5532) This explains so much of the GLP-1 non-responder data

The exception: if you take insulin or sulfonylureas alongside your GLP-1 medication