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Current strategies focus not only on targeting the BBB endothelium but also on the effective transport of specific compounds across it and the subsequent targeted drug release at appropriate targets in the brain (32)

B12 is a water-soluble vitamin, so anything the body cannot use immediately is excreted in urine

Clinical trials are a critical step in the development of new treatments, serving to assess their efficacy and safety before receiving market approvals, yet they also represent the most resource-intensive and operationally complex stage 4

Its defined structural profile supports reproducible molecular interaction studies

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