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At low concentrations of NAPQI, a slight increase in proliferation, suggestive of hormesis, was observed in many of the cell lines (see Fig

Kayima J, Liang J, Natanzon Y, Nankabirwa J, Ssinabulya I, Nakibuuka J, et al

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These nodules often coexist with uterine adenomyosis, with external uterine adenomyosis detected in over 97% of women with deep posterior endometriotic nodules 3 cm

That results in stable DNA adducts and can slow estrogen-sensitive cell growth and even reverse DNA damage caused by the 4-OHE1 pathway of Phase I metabolism