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Riboflavin is also a co-factor for pyridoxine phosphate oxidase, the enzyme required for vitamin B6 production (as pyridoxal 5-phosphate) which is, in turn, an essential cofactor for the enzymes cystathionine-b-synthase (required for the conversion of homocysteine to cysteine) and cystathionine g-lyase (required for the conversion of cysteine to glutathione)

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Furthermore, an independent meta-analysis concluded that probiotic supplementation effectively augments the immunogenic response to influenza vaccination in adults (516)

As of March 2026, more than 3,363 lawsuits have been filed across both MDLs