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While this is a key research area, we propose that further investigations should verify whether GLP-1RAs may also affect cognitive and behavioral symptoms seen in psychosis, as suggested by their potential to influence neurobiological (for example, immune function) and neuropsychological (for example, reward) mechanisms that are known to be disrupted in psychotic illness

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Tirzepatide is sold as Mounjaro for T2D and Zepbound for obesity in the US, and the two brands grew 110% and 123% to $7.41 billion and $4.26 billion, respectively, in the last quarter of 2025, year-on-year

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