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Therefore, we tested this concept in vivo where we showed 7 days of L-citrulline combined with GSH supplementation to increase plasma L-citrulline and L-arginine levels

10.1210/er.2009-0033 Endocr

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In addition, getting at least 8 hours of quality sleep each night is essential for not only stress reduction but for detoxification and healing when we have something such as MTHFR