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Enzymatic degradation by proteases and chemical instability can limit therapeutic effectiveness and require specialized storage and handling procedures

Glutathione is concentrated inside these structures precisely because it neutralizes those byproducts

That kind of follow-up turns a transaction into a relationship

Intensive protocols require closer medical monitoring to ensure appropriate tolerance and to assess therapeutic response

This highlights the need for strategies to overcome the restrictive nature of the BBB and the lack of drug targeting specificity which hinder delivery of adequate drug concentrations in the affected brain regions