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In summary, MTNs provide synchronized and high-precision sensory coding, whereas TMNs ensure continuous and controlled motor output, forming a complementary sensorimotor partnership

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In a rat model of FM induced by reserpine, treatment with honokiol reduced pain, depression and anxiety, increased SOD and IL-10 levels, and decreased MDA, TNF- and prostaglandin E 2 (PGE 2 ) levels