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Human and animal blood also contain relatively high levels of glutathione, while its content in plant tissues is generally lower

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As electrons are passed down this chain, they release energy that is used to pump protons across the membrane, creating an electrochemical gradient

CB-839 was very well tolerated in heavily pretreated patients, with mostly mild (grade 1 or 2) adverse effects such as nausea, fatigue, photophobia, mild liver function elevation, diarrhea, and rash [170]