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South Florida patients, particularly those in the Fitzpatrick III through VI range who have higher baseline melanin activity and different wound healing patterns, sometimes see post-inflammatory hyperpigmentation respond more slowly than texture or firmness

For laboratory researchers, this is the central issue

doi: 10.1146/annurev.arplant.49.1.249 51 NoctorG.GomezL.VanackerH.FoyerC