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Common signs and symptoms include Skin reactions, including hives and itching and flushed or pale skin Wheezing and breathing trouble Slurred speech Shock Nausea, vomiting or diarrhea Low blood pressure (hypotension) Facial swelling Dizziness or fainting Difficulty swallowing Constriction of airways and a swollen tongue or throat Anxiety and confusion Abdominal pain A weak and rapid pulse There are not many known risk factors for anaphylaxis, but certain things may increase the potential risk associated with the condition and these include previous anaphylaxis, allergies or asthma and certain other conditions (like heart disease and an abnormal accumulation of a certain type of white blood cell (mastocytosis)

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Data were collected using a TimsTOF HT (Bruker Daltonics) coupled to a nanoElute LC pump (Bruker Daltonics) by a CaptiveSpray nanoelectrospray source