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In clinical research, it has been observed to increase sexual desire scores in both male and female populations

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When taken properly to reach the target cumulative dose, Accutane provides long-lasting results for most patients

In certain embodiments, any controlled release otic formulation or composition described herein increases the exposure of a therapeutic agent and increases the Area Under the Curve (AUC) in otic fluids (e.g., endolymph and/or perilymph) by about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, or about 90% compared to a formulation or composition that is not a controlled release otic formulation or composition

Lee IA, Low D, Kamba A, Llado V, Mizoguchi E