sadly, many patients develop severe fatal outcomes because of overwhelming inflammation known as cytokine storm (248, 249), that leads to ROS-mediated cell death and tissue damage typical of RNA viruses (250)
The inflammatory phase involves vasodilation due to histamine and serotonin release from mast cells as well as granulocyte and monocyte migration
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Yet, we need it it is vitally important to our bodys ability to manage oxidative stress among other things
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