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This could point to differing effects in human patients, for instance, between pre- and postmenopausal women, said Hayes

11 Peripheral clocks exist in nearly every organ system, including the brain, heart, gastrointestinal tract, pancreas, adipose tissue, adrenal glands, lungs, skeletal muscle, kidneys, and submandibular glands

One patient (4303) exhibited no discernible reaction, potentially due to an absence of immunogenic epitopes

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The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest