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Furthermore, while antibiotic lethality correlates with cellular metabolism 24,25,29 , we note here that the observed protection from antibiotic killing by glutathione did not arise from differences in intracellular ATP levels, as indicated by bulk-culture measurements of ATP abundance (Supplementary Fig

These hallmarks of aging satisfy three conditions: (i) they become apparent with advancing age, (ii) experimentally perturbing them causes poor aging (iii) therapeutically intervening upon them prevents, delays or reverses aging phenotypes

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12 In December 2025, high-dose oral semaglutide (Wegovy) became the first orally administered GLP-1 RA approved for obesity treatment, providing a noninjectable alternative within the IBT class