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This type of evaluation becomes especially important in cases for which the APAP-associated liver failure was a consequence of intentional ingestion, as a repeat episode of over-ingestion will inevitably cause harm to the transplanted organ and squandering of a limited resource

Time zone changes may affect the weekly dosing schedule, and patients should plan how to maintain consistent seven-day intervals between doses while accommodating their travel schedule

3.2 Patient-reported outcome measures (PROMs) As summarized in Table 2, HA + GSH-C4 treatment was associated with a reduction in OSDI scores (control formulation: 25.26 0.05 vs