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Franchi et al., 2009

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[22] A case series of 15 patients from India treated with a GSH-containing soap for melanosis of the face reported lightening (in 11/15 after 3 months) based on clinical photographs

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Furthermore, excessive activation of mTOR inhibits autophagy during spermatogenesis, affecting the clearance of defective cells and the homeostasis of the intracellular environment, which in turn impacts sperm production [234,235,236]