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At present, the available evidence suggests that both GLP-1 agonist and SGLT2 inhibitors produce unfavourable outcomes, and should be avoided in pregnancy and during lactation

It separately says pre-existing dysbiosis or IBS should be assessed before adding anything

Conclusion The FDA's ruling on Semaglutide, effective as of April 7, 2025, poses significant changes for aesthetics practices, requiring a shift to branded medications by mid-2025, subject to legal outcomes

The effect is mostly temporary and is observed in the first weeks of treatment as the body adapts to the effect of the medication on the blood sugar and appetite

Somatostatin analogues such as octreotide inhibit GLP-1 and insulin release