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Importantly, these phenotypes frequently coexist, so that many high-risk patients qualify for both classes, necessitating integrated and often combination-based treatment strategies (Fig

Sin embargo, los descubrimientos tempranos tambin mostraron que el GLP-1 tena una presencia significativa en el cerebro de roedores, lo que sugera un papel potencial en la regulacin del apetito y la ingesta de alimentos

Whilst RCTs have reported DKA ranging from 0.84.3% [34], real-world rates of DKA have ranged from 0.0 [38]3.5% [25] with one outlier of 12.5% [14]

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Supporting this, Vojdani et al