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Areas Requiring Further Investigation Further research is needed to clarify long-range receptor signaling behavior, tissue-specific pathway effects, molecular signaling durability, model-to-human translation, and how findings vary across study designs

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Exendin-4 was eventually developed into exenatide, a treatment for diabetes and the first GLP-1 receptor agonist approved for medical use

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Exenatide Once Weekly for Alcohol Use Disorder Investigated in a Randomized, Placebo-Controlled Clinical Trial